Activated Partial Thromboplastin Time (APTT)

Coagulation

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Description

APTT is a screening test for the Intrinsic and Common Pathways of the Coagulation cascade. A modified APTT ( APTT RATIO ) is used to monitor unfractionated heparin.

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Indications

In isolation, or as part of a full clotting screen as a general assessment of haemostasis and/or thrombosis

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Sample Type

Plasma ( Citrate 2.7ml Blue ) x 1

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Reference Range

Reference range may vary with reagent batches. Adult reference range current at time of testing is indicated on the report.

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Turnaround Time

Within 1 hour

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Testing Frequency

Daily/continuous processing 24hrs

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External Notes

The accuracy of all coagulation tests is greatly influenced by pre analytical variables. It is essential that sample quality is given the highest of priorities. Samples which fail to meet quality criteria including age of sample, specimen fill ( >90% ), haemolysed, clotted or activated samples will be rejected and a repeat sample requested.

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Patient Preparation

No special requirements.

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References

Guidelines on the Laboratory aspects of assays used in haemostasis and thrombosis Mackie I, Cooper P, Lawrie A, Kitchen S, Gray E, Laffan MCLSI. Collection, Transport and Processing of Blood Specimens for Testing Plasma-based Coagulation Assays and Molecular Haemostasis Assays. Approved Guideline - Fith Edition. CLSI document H21-a5 [ISBN 1-56238-657-3]. CLSI, 940 West Valley Rd., Suite 1400 Wayne, Pennsylvania 19087-1898 USA, 2008

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See Also

APTT RATIO

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.