Clinical Chemistry

Leading edge pathology conducted by a dedicated team of highly trained, skilled and specialised scientists

Clinical Chemistry

Our experienced team provide a wide range of routine and specialist chemistry testing including toxicology.  We provide a specialist service for the assay of a variety of steroid and peptide hormones, biogenic amines, bone markers and trace metals. We provide scientific expertise in support of the national Choriocarcinoma Screening Service. Our Toxicology team provides forensic and non-forensic toxicology services to a significant number of coroners across the UK.

If you would like to know more about how we can help you, please contact us by telephone on 0114 226 7666 or email us at sth.labmed@nhs.net

Department Specific Tests

17a Hydroxyprogesterone

25-Hydroxy Vitamin D (Vitamin D)

5-Hydroxyindole Acetic Acid, 5HIAA (Urine)

7-Dehydrocholesterol (Smith Lemli Opitz Syndrome)

ACTH

Acute Kidney Injury

Acylcarnitine profile

Alanine Transaminase (ALT SGPT)

Albumin

Albumin:creatinine ratio

Alcohol

Alkaline Phosphatase

Alkaline Phosphatase Isoenzymes

Aluminium

Amino Acids (quantitative) or Branched Chain Amino Acids (isoleucine, alloisoleucine, leucine, valine)

Amitriptyline and Nortriptyline

Ammonia, NH3

Amylase Isoenzymes

Androstenedione

Angiotensin Converting Enzyme (ACE)

Anti-Mullerian Hormone (AMH)

Aspartate Aminotransferase (AST, SGOT)

Assays for Gentamicin, Tobramycin, Vancomycin and Teicoplanin

Bicarbonate

Bile Acids (3a-hydroxy bile acids)

Bilirubin (Total, Conjugated (Direct) )

Biotinidase

Blood Gases (ABG)

Bone Alkaline Phosphatase (Bone ALP)

Buprenorphine

C-Peptide

C-Reactive Protein (CRP)

Calcium

Carbamazepine

Carboxyhaemoglobin / Carbon Monoxide

Carnitine

Catecholamines ( Adrenaline, Noradrenaline and Dopamine)

Chloride

Cholestanol

Copper

Cortisol

Creatine Kinase (CK)

Creatinine

CSF Bilirubin (Xanthochromia)

Cyclosporin/Ciclosporin (CYA, CSA)

Dehydroepiandrosterone Sulphate (DHEAS)

Digoxin

Drugs of Abuse Screen: opiates, methadone, EDDP, amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine metabolites, buprenorphine, norbuprenorphine

Ethanol

Ethylene Glycol

Ferritin

Folate (Serum)

Follicle Stimulating Hormone (FSH)

Free Androgen Index (FAI)

Free T3

Free T4

Galactosaemia screen (Galactose -1- phosphate uridyl transferase)

Gamma glutamyl transferase (GGT)

Globulin

Glucose

Glycosaminoglycans (Mucopolysaccharides, MPS)

Growth Hormone

HFE Haemochromatosis genetics

High sensitivity Troponin T

Homocysteine and Methionine

Human Chorionic Gonadotropin (HCG)

Insulin

Insulin-Like Growth Factor (IGF-1)

Intermediary Metabolites (Free Fatty Acids, 3-hydroxybutyrate)

Iron, TIBC, Transferrin Saturation, Iron Profile

Lactate Dehydrogenase (LDH)

Lactic Acid (Lactate)

Lamotrigine

Lead

Lipase

Lipids (Cholesterol, triglycerides, HDL)

Lipoproteins: lipoprotein (a)

Lithium

Luteinising Hormone (LH)

Metanephrines

Methanol

Methotrexate

Methylmalonate (urine or plasma)

N-Telopeptide (NTX)

Neonatal Routine Chemistry

Oestradiol (E2)

Organic Acids Profile

Orotic acid

Osmolality

Pancreatic Faecal Elastase-1

Paracetamol

Paraquat and Diquat

Parathyroid Hormone (PTH)

Phenobarbital

Phenylalanine

Phenytoin (Epanutin)

Phosphate

Phytosterols ( inc. sitosterol, campesterol, stigmasterol )

Porphobilinogen (PBG) in Urine: Acute Porphyria

Potassium

Progesterone

Prolactin

Protein (CSF)

Protein (urine):- Protein:creatinine ratio (PCR) or 24 hour urine protein

Salicylate

Selenium

Sex Hormone Binding Globulin (SHBG)

Sirolimus

Smith Magenis Test

Sodium

Tacrolimus (FK506)

Testosterone

Theophylline (Aminophylline)

Thyroid Stimulating Hormone (TSH)

Total Procollagen Type-1 N-Terminal Propeptide/Procollagen Extension Peptide (P1NP)

Total Protein

Toxicology / Drug Screen in Suspected Poisoning

Trimethylamine and Oxide (Fish Odour Syndrome)

Urea

Uric Acid (Urate)

Valproate

Very Long Chain Fatty Acids (VLCFA)

Vitamin B12 (serum)

Vitamin K

Zinc