Clinical Chemistry
Leading edge pathology conducted by a dedicated team of highly trained, skilled and specialised scientists
Clinical Chemistry
Our experienced team provide a wide range of routine and specialist chemistry testing including toxicology. We provide a specialist service for the assay of a variety of steroid and peptide hormones, biogenic amines, bone markers and trace metals. We provide scientific expertise in support of the national Choriocarcinoma Screening Service. Our Toxicology team provides forensic and non-forensic toxicology services to a significant number of coroners across the UK.
If you would like to know more about how we can help you, please contact us by telephone on 0114 226 7666 or email us at sth.labmed@nhs.net
Department Specific Tests
1, 25 Di-Hydroxy Vitamin D ( Active 1,25 Vitamin D )
25-Hydroxy Vitamin D (Vitamin D)
5-Hydroxyindole Acetic Acid, 5HIAA (Urine)
7-Dehydrocholesterol (Smith Lemli Opitz Syndrome)
Alanine Transaminase (ALT SGPT)
Aldolase B mutation (Hereditary Fructose Intolerance)
Alkaline Phosphatase Isoenzymes
Amiodarone with desethylamiodarone
Amitriptyline and Nortriptyline
Angiotensin Converting Enzyme (ACE)
Antidiuretic hormone (Arginine Vasopressin AVP, ADH)
Aspartate Aminotransferase (AST, SGOT)
Assays for Gentamicin, Tobramycin, Vancomycin and Teicoplanin
Bile Acids (3a-hydroxy bile acids)
Bilirubin (Total, Conjugated (Direct) )
Bone Alkaline Phosphatase (Bone ALP)
Calcitonin (Charing Cross Assay, STH requests)
Carboxyhaemoglobin / Carbon Monoxide
Carotenoids (alpha-carotene, beta-carotene)
Catecholamines ( Adrenaline, Noradrenaline and Dopamine)
Cortisol and cortisone (salivary)
Cyclosporin/Ciclosporin (CYA, CSA)
Dehydroepiandrosterone Sulphate (DHEAS)
Diuretic screen: Thiazides, Indapamide, Frusemide
Enhanced Liver Fibrosis Test (ELF)
Familial Hypercholesterolaemia (FH) Genetics
Fibroblast Growth Factor 23 (FGF23)
Follicle Stimulating Hormone (FSH)
Galactosaemia screen (Galactose -1- phosphate uridyl transferase)
Galactose-1-phosphate, Galactose-1-phosphate uridyl transferase (quantitative) and Galactokinase
Gamma glutamyl transferase (GGT)
Glycosaminoglycans (Mucopolysaccharides, MPS)
Holotranscobalamin (Active B12)
Human Chorionic Gonadotropin (HCG)
IGF Binding Protein 3 ( IGFBP3 )
Insulin-Like Growth Factor (IGF-1)
Insulin-like growth factor II (IGF-II)
Intermediary Metabolites (Free Fatty Acids, 3-hydroxybutyrate)
Iron, TIBC, Transferrin Saturation, Iron Profile
Lipids (Cholesterol, triglycerides, HDL)
Lipoproteins: lipoprotein (a), apolipoprotein (a) or lipoprotein (X)
Liver biopsy for copper or iron quantitation
Macro Creatine Kinase (Macro CK)
Methylmalonate (urine or plasma)
Neurotransmitters (CSF) (monoamine metabolites)
Oxysterol (Neimann-Pick type C)
Parathyroid Hormone Related Peptide (PTH rP)
Phytosterols ( inc. sitosterol, campesterol, stigmasterol )
Pituitary polypeptide - alpha subunit
Porphobilinogen (PBG) in Urine: Acute Porphyria
Porphyrin tests: Cutaneous Porphyria
Protein (urine):- Protein:creatinine ratio (PCR) or 24 hour urine protein
Sex Hormone Binding Globulin (SHBG)
Thioguanine nucleotides/thiopurine metabolites ( 6TGN & 6MMPN )
Thiopurine Methyl Transferase (TPMT)
Thyroid Stimulating Hormone (TSH)
Total Procollagen Type-1 N-Terminal Propeptide/Procollagen Extension Peptide (P1NP)
Toxicology / Drug Screen in Suspected Poisoning
Transferrin Glycoforms ( isoelectric focusing )
Trimethylamine and Oxide (Fish Odour Syndrome)
Very Long Chain Fatty Acids (VLCFA)
Vitamin B6 ( Pyridoxine - Pyridoxal phosphate and isomers )
Vitamin C (Plasma Ascorbic acid)