Amitriptyline and Nortriptyline

Clinical Chemistry

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Description

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Indications

Therapeutic monitoring of amitriptyline in blood samples is generally limited to cases where compliance is an issue. Although there is considerable inter-individual variation in blood levels for the same dose, measurement of blood concentrations (therapeutic drug monitoring) is rarely indicated. Measurement of blood amitriptyline and nortriptyline concentrations are not useful in cases of confirmed or suspected overdose.

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Sample Type

Serum (at least 2 mL)

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 14 days

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Testing Frequency

as required

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External Notes

Amitriptyline is usually prescribed as a generic formulation.  Proprietary names have included Triptafen.

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Patient Preparation

Ideally take pre-dose (trough) sample.

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Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.