Alkaline Phosphatase Isoenzymes

Clinical Chemistry

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Description

Alkaline phosphatase isoenzymes are used to identify the source of a raised alkaline phosphatase when aetiology is uncertain. Please note, interpretation can be difficult if total ALP activity is only slightly elevated. Fasting samples are preferred. Some patients with blood group O or B may have increased ALP activity after meals (intestinal form).

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Indications

Raised total ALP without clear cause. If bone disease is suspected, measurement of specific markers of bone turnover may be more appropriate. In children and adolescents, please check that ALP is truly increased above the age-related reference range before requesting this test.

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Sample Type

Serum, SST/Gel. Minimum 2 mL (1 mL separated serum)

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 3 weeks

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Testing Frequency

Fortnightly

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External Notes

In children and adolescents, please check that ALP is truly increased above the age-related reference range before requesting this test.

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Patient Preparation

Fasting samples preferred. Some patients with blood group O or B may have increased ALP activity after meals (intestinal form).

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See Also

Bone specific alkaline phosphatase

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.