Anti-Mullerian Hormone (AMH)

Clinical Chemistry

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Description

AMH is a member of the transforming growth factor-β ( TGF-β ) family. In women, it is produced primarily by the pre-antral and small antral follicles of the ovary. It declines slowly with age, reaching undetectable levels at menopause. Anti-mullerian hormone is associated with oocyte yield after ovarian stimulation. Pre-treatment AMH can be used to individualise treatment strategies for controlled ovarian stimulation ( COS ).

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Indications

Currently available to Department of Obstetrics and Gynaecology, in the work-up of patients for assisted conception, and the STH Endocrinologists. Requests on women from Laboratories outside Sheffield Teaching Hospitals also accepted. Our test is not done on men, children or neonates ( samples would need to be referred ).

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Sample Type

Serum, SST/Gel. Minimum 2 mL ( 1 mL separated serum ). Separate serum within 4 hours of collection. Stable for 3 days at 20-25C, 5 days at 2-8C, 6 months at -20C. Therefore samples can be sent by 1st class post if received at STH within 3 days of collection and are not subject to extremes of temperature. Otherwise deliver frozen. Avoid repeat freeze-thaw cycles. Avoid posting samples towards the end of the week. Grossly haemolysed samples are unsuitable.

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 10 days

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Testing Frequency

Weekly

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Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.