Aspartate Aminotransferase (AST, SGOT)

Clinical Chemistry

---

Description

Aspartate aminotransferase ( AST ) is a pyridoxal phosphate ( PLP )-dependent transaminase enzyme found in high concentrations in liver, skeletal muscle, heart, kidney and red blood cells. Therefore, even though it is often requested as a marker of liver inflammation, it is non-specific for the liver. Other causes of a raised AST include skeletal muscle disease, trauma, myocardial infarction and haemolytic anaemia. AST is present in both the cytoplasm and mitochondria of cells.

---

Indications

Usually as part of a liver function test profile

---

Sample Type

Serum. SST/Gel, Minimum 2mL (1mL separated serum). Avoid haemolysis

---

Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

---

Turnaround Time

Within 1 day

---

Testing Frequency

Daily

---

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.