Cardiac Muscle Antibodies

Immunology


Description

Cardiac muscle antibodies are described in patients with Dressler's syndrome after myocardial infarction, cardiomyopathy, myocarditis and in patients who have undergone cardiac surgery or have had rheumatic fever. They can be directed towards a number of antigens such as adenine nucleotide translocator protein, cardiac myosin and tropomysin. The presence of antibodies can occur without the Dressler syndrome.


Indications

Dressler's syndrome, post-MI.


Sample Type

2mL Serum (Gel 5mL Yellow tube). Requests from outside Sheffield: Transport at ambient temperature via Royal Mail or Courier.


Reference Range

Normal result = Negative.


Turnaround Time

Within 10 days


Testing Frequency

Weekly


References

Jahns R, Boivin V, Schwarzbach V et al. Pathological autoantibodies in cardiomyopathy. Autoimmunity. 2008. 41(6):454-461. [Ref 1]
Okasaki T, Honjo T. Pathogenic roles of cardiac autoantibodies in dilated cardiomyopathy. Trends Mol Med. 2005. 11(7):322-326. [Ref 2]
Caforio AL, Daliento L, Angelini A et al. Autoimmune myocarditis and dilated cardiomyopathy: focus on cardiac autoantibodies. Lupus. 2005. 14(9):652-655.


See Also

Skeletal muscle

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.

Your contact for this test

team

Clare Del-Duca BSc (Hons) Biomedical Science, MSc Pathological Science

Laboratory Manager - Immunology and Protein Reference Unit

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Cardiac Muscle Antibodies