Copper

Clinical Chemistry

---

Description

Serum copper is often measured with zinc and selenium in patients undergoing nutritional assessment. Where a metabolic disease is suspected, it should be requested with caeruloplasmin. Copper is an essential trace element. It circulates bound to caeruloplasmin and is also stored in the liver. Copper deficiency is rare in adults but may present with a microcytic anaemia unresponsive to iron treatment, neutropenia and osteoporosis. Acute ingestion of copper salts produces nausea, vomiting, diarrhoea, dizzyness and intravascular haemolysis.

---

Indications

Suspected Wilsons disease, Menke's disease, patients on long-term TPN or biliary fistula. Suspected toxicity.

---

Sample Type

Trace metal tube preferred. Serum, SST/Gel or plasma, EDTA also suitable, minimum 2 mL (400uL separated serum/plasma). 24 hour or random urine, plain or acid container (NOT boric acid), minimum 5 mL

---

Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

---

Turnaround Time

Within 2 weeks

---

Testing Frequency

Serum: weekly.
Urine: weekly

---

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.