Growth Hormone

Clinical Chemistry

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Description

GH is synthesised by the anterior pituitary following stimulation by GHRH (growth-hormone-releasing hormone) and somatostatin. GH stimulates the liver to produce insulin-like growth factor-1 (IGF-1), which subsequently exerts negative feedback on the pituitary and hypothalamus. GH is important for growth and has many other metabolic actions, including stimulation of lipolysis, protein synthesis and hepatic glucose production.

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Indications

Growth hormone deficiency, gigantism, acromegaly, as part of a dynamic function test

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Sample Type

Serum, SST/Gel, minimum 2 mL (1mL separated serum).

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 3 days

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Testing Frequency

As required

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Patient Preparation

As required for dynamic test protocol

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