Immunoglobulin Immunofixation

Immunology

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Description

See Immunoglobulins.

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Indications

Myeloma / LPD / Immunodeficiency / paraprotein neuropathy (POEMS, MMN etc), AL Amyloidosis.

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Sample Type

2mL Serum (Gel 5mL Yellow tube). Requests from outside Sheffield: Transport at ambient temperature via Royal Mail or Courier.

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Reference Range

Concentration (g/L), isotype & comment reported.

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Turnaround Time

Within 5 days

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Testing Frequency

Daily

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External Notes

See Immunoglobulins.

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References

Smith A et al. Guidelines on the diagnosis and management of multiple myeloma 2005. Br J Haem. 2006. 132:410-51.Wuyts B, Bossuyt X, Verhoef G, Blanckaert N, Delanghe JR. Conflicting results between electrophoresis methods of serum M-proteins. Electrophoresis. 2004. 25:1548-1550. Manual of Clinical Laboratory Immunology. 6th Edition. Keren. D.F. Imunoglobulin Quantitation. 92 - 97; ASM Press 2002Rajkumar S, et al. International myeloma working group updated criteria for the diagnosis of multiple myeloma. 2014. Lancet Oncology, 15:e538-548.Bird JM, et al. Guidelines for the diagnosis and management of multiple myeloma 2014. 2014. British Committee for Standards in Haematology (BCSH), UK myeloma Forum.

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See Also

Immunoglobulins

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.