Lactic Acid (Lactate)

Clinical Chemistry

---

Description

Lactate is generated by anaerobic glycolysis, mainly in skeletal muscle, the brain, skin, the gut, and erythrocytes. It is disposed of mainly through gluconeogenesis in the liver and kidney, therefore providing an important source of glucose. Blood lactate measurements are usually used in the investigation of metabolic acidosis. However measurement is only indicated if the type of acidosis is not apparent from the clinical context. Measurements of lactate in blood and CSF may be of value in the investigation of suspected mitochondrial disorders, although neither is invariably raised.

---

Indications

Investigation of metabolic acidosis where lactic acidosis is suspected. Investigation of mitochondrial disorders.

---

Sample Type

Plasma, Fluoride oxalate ( grey top ), 5 mL

---

Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

---

Turnaround Time

Within 1 day

---

Testing Frequency

As required.

---

Patient Preparation

Blood samples should be drawn from a stasis-free vein. However, minimal hemostasis ( less than 30 seconds ) will not affect lactate levels. Avoid the use of a tourniquet, if possible.

---

Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.