Pancreatic Faecal Elastase-1

Clinical Chemistry

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Description

Human pancreatic elastase-1 has a unique structure that resists degradation in the GI tract. The ScheBo elastase assay is a test of pancreatic exocrine function. It is more convenient for patients than the pancreolauryl test and does not require discontinuation of enzyme supplements. At a cut-off of 200 ug/g it was reported to detect most cases of �moderate' and �severe' pancreatic insufficiency and 20-50% of �mild' cases. A result less than 100 ug/g faeces suggests severe pancreatic insufficiency, but patients with other GI diseases (especially if there is diarrhoea) may have low results.

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Indications

Suspected exocrine pancreatic insufficiency. This test may not detect all cases of mild pancreatic insufficiency.

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Sample Type

Random pea-sized particle of faeces (preferably formed)

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 10 days

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Testing Frequency

weekly

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Patient Preparation

Patients collect a pea-sized particle of faeces in to a container. It is not necessary to discontinue medication such as enzyme supplements.

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Please note: the above information is subject to change and we endeavour to keep this website up to date wherever necessary.