Urea

Clinical Chemistry

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Description

Urea is the major end product of protein nitrogen metabolism. It is synthesized by the urea cycle in the liver from ammonia which is produced by amino acid deamination. Urea is excreted mostly by the kidneys but minimal amounts are also excreted in sweat and degraded in the intestines by bacterial action. The serum urea concentration depends on the protein/nitrogen intake.

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Indications

Forms part of a urea and electrolytes (U&E) profile. To evaluate renal function. When used in conjunction with serum creatinine determinations it can aid in the differential diagnosis of the three types of renal impairment: prerenal, renal and postrenal.

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Sample Type

Serum, SST/Gel, minimum 2 mL (1 mL separated serum).

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Reference Range

Reference ranges are provided on the report. Alternatively, please contact the laboratory for current ranges.

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Turnaround Time

Within 1 day

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Testing Frequency

As Required

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