VWF Antigen (VWF:Ag)

Coagulation

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Description

VWF serves two functions in haemostasis, as a carrier protein for FVIII and as a bifunctional ligand mediating platelet GP1b a adhesion to collagen. VWF in plasma is detectable immunologically as VWF:Ag. A reduction in VWF activity results in von Willebrand Disease ( VWD ). The VWF:Ag may be within normal limits in some types of VWD.

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Sample Type

Plasma ( Citrate 2.7ml Blue ) x 2

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Reference Range

Current reference range is indicated on the report.

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Turnaround Time

Within 2 weeks

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Testing Frequency

weekly

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References

current method is a modification of the method below.Silveira AMV et al ( 1986 ). Application of an ELISA to VWF and its derivatives. Thromb Res, 43, 91-102

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See Also

See also Chromogenic VIII, VWF ANTIGEN ( VWF:Ag ), VWF Activity ( VWF:Act )

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